Curcumin is the primary bioactive substance in turmeric, and has anti-inflammatory properties and decent evidence for indications from chronic pain to depression. Curcumin exhibits antioxidant, anti-inflammatory and anti-cancer properties, crosses the blood-brain barrier and is neuroprotective in neurological disorders. Several studies in different experimental models of Parkinson’s Disease strongly support the clinical application of curcumin in Parkinson’s Disease.

Curcumin  has poor bioavailability alone, necessitating special formulations to be efficiently absorbed.

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